Artificer: Chunked!

 is a challenge in Risk of Rain 2. It is completed as Artificer by fully defeating a Teleporter Boss in a one-second burst of damage.

Tips

 * One way of getting this challenge would be to get the from the Timed Security Chest while getting damage items like some humble combination of,  and . With these items a synchronized Preon and Charged Nano-Bomb attack would easily kill a single boss-enemy in an instant. This challenge becomes nearly impossible with this setup when multiple boss-enemies spawn. Playing on Drizzle would make single-enemy bosses spawn for more stages. If too much time passes and multiple enemy bosses start spawning it would probably be easier to just start another run.
 * Another viable option is to start the run on Drizzle and use the Command Artifacts to stack at several (at least 5), plus a few  the first and second stage and repeatedly reset until the first boss drops a boss item from which you choose . Then during the second teleporter event allow the boss to hit you until Genesis Loop procs and it should instantly kill the boss, one benefit of this method is you do not need to spend Lunar Coins, though getting a boss item on stage one is inconsistent.
 * Similarly, instead of a boss item, using both the and, it is possible to "chunk" the first boss if you continually choose the  from the white chests. Upon activating the teleporter, as long as you have at least 4 crowbars (on drizzle, other difficulties will need more) a single fully charged Charged Nano-Bomb will one-shot the boss.