Artificer: Chunked!

 is a challenge in Risk of Rain 2.

Tips

 * One way of getting this achievement would be to get the Preon Accumulator from the Timed Security Chest while getting damage items like some humble combination of Armor-Piercing Rounds, Crowbar and Shaped Glass. With these items a synchronized Preon and Charged Nano-Bomb attack would easily kill a single boss-enemy in an instant. This challenge becomes nearly impossible with this setup when multiple boss-enemies spawn. Playing on Drizzle would make single-enemy bosses spawn for more stages. If too much time passes and multiple enemy bosses start spawning it would probably be easier to just start another run.